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CAR-T Cell
Therapy

      CAR-T Cell Therapy

      CAR-T Cell Therapy at Mar Sleeva Medicity Palai represents a new era in cancer treatment. As one of the most advanced forms of immunotherapy, CAR-T cell therapy provides hope to patients with relapsed or treatment-resistant blood cancers who have limited options with conventional treatments.

      CAR-T (Chimeric Antigen Receptor T-cell) therapy involves collecting a patient's own T cells, genetically modifying them to recognize and attack cancer cells, and infusing them back into the patient.

      The process involves:

      • T Cell Collection : A sample of the patient’s T cells (a type of white blood cell) is collected through a procedure called leukapheresis.
      • Genetic Modification : In a specialized laboratory, the T cells are engineered to express a receptor (CAR) that targets cancer cells.
      • Expansion : The modified cells are multiplied until there are millions of CAR-T cells ready for therapy.
      • Infusion : The CAR-T cells are infused back into the patient’s bloodstream, where they seek out and destroy cancer cells.

      This “living drug” continues to expand and work inside the body, offering long-term protection against cancer recurrence.

      Conditions Treated

      CAR-T cell therapy is primarily used in patients with:

      • Acute Lymphoblastic Leukemia (ALL) : especially in children and young adults who relapse after standard treatments
      • Relapsed or Refractory Lymphomas : including Diffuse Large B-Cell Lymphoma (DLBCL)
      • Chronic Lymphocytic Leukemia (CLL) : in select resistant cases
      • Ongoing research and trials continue to expand its use to other cancers
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      Why Choose Mar Sleeva Medicity Palai?

      • Specialized Infrastructure: Advanced cell-processing laboratories and protective patient-care units designed for intensive monitoring.
      • Expert Multidisciplinary Team: Hemato-oncologists, immunotherapy specialists, genetic scientists, and critical care experts work together for safe and effective outcomes.
      • Cutting-edge Monitoring: Continuous patient observation for early detection and management of therapy-related side effects, such as cytokine release syndrome (CRS).
      • Comprehensive Supportive Care: Includes infection prophylaxis, transfusion services, rehabilitation, and psychological counseling.
      • Global Protocols, Local Access: Treatment protocols adhere to international standards while remaining accessible to patients in India.

      The Treatment Journey

      • Evaluation & Eligibility : Careful assessment of medical history, disease status, and overall health.
      • Cell Collection & Engineering : T cells are harvested and genetically modified using advanced laboratory processes.
      • Conditioning Therapy : Low-dose chemotherapy prepares the body for CAR-T infusion.
      • CAR-T Infusion : Modified cells are returned to the patient’s body in a single infusion.
      • Monitoring & Recovery : Intensive observation for immune responses and side effects, followed by rehabilitation and long-term follow-up.
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      Long-Term Follow-Up

      CAR-T therapy requires ongoing monitoring to:

      • Ensure continued effectiveness of infused CAR-T cells
      • Detect and manage late side effects
      • Support immune system recovery with vaccination schedules and infection control
      • Provide psychological and nutritional support for holistic recovery

      Safety and Expertise

      Our sarcoma surgeries are performed with strict adherence to oncological safety principes, advanced operative technology, and multidisciplinary support. The team ensures maximal tumor removal while preserving limb and organ function.

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      Frequently asked Questions

      Geriatricians have dedicated advanced training in the aging process. They excel at managing how multiple health issues interact with one another and focus heavily on preserving mobility, cognitive function, and quality of life rather than just treating isolated symptoms.

      Our geriatric team manages a wide range of age related health concerns. This includes memory disorders such as dementia, mobility and balance issues, chronic joint pain, osteoporosis, fall prevention, and the comprehensive management of complex overlapping diseases.

      While there is no strict age requirement, adults aged 65 and older generally benefit the most from this specialized care. It is especially recommended for seniors who are managing multiple chronic conditions, experiencing memory issues, or taking several daily medications.

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      Affordable Treatment

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      We provide the most affordable treatment in the health sector.

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      Critical Medical Care

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