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CAR-T Cell
Therapy

      CAR-T Cell Therapy

      CAR-T Cell Therapy at Mar Sleeva Medicity Palai represents a new era in cancer treatment. As one of the most advanced forms of immunotherapy, CAR-T cell therapy provides hope to patients with relapsed or treatment-resistant blood cancers who have limited options with conventional treatments.

      CAR-T (Chimeric Antigen Receptor T-cell) therapy involves collecting a patient's own T cells, genetically modifying them to recognize and attack cancer cells, and infusing them back into the patient.

      The process involves:

      • T Cell Collection : A sample of the patient’s T cells (a type of white blood cell) is collected through a procedure called leukapheresis.
      • Genetic Modification : In a specialized laboratory, the T cells are engineered to express a receptor (CAR) that targets cancer cells.
      • Expansion : The modified cells are multiplied until there are millions of CAR-T cells ready for therapy.
      • Infusion : The CAR-T cells are infused back into the patient’s bloodstream, where they seek out and destroy cancer cells.

      This “living drug” continues to expand and work inside the body, offering long-term protection against cancer recurrence.

      Conditions Treated

      CAR-T cell therapy is primarily used in patients with:

      • Acute Lymphoblastic Leukemia (ALL) : especially in children and young adults who relapse after standard treatments
      • Relapsed or Refractory Lymphomas : including Diffuse Large B-Cell Lymphoma (DLBCL)
      • Chronic Lymphocytic Leukemia (CLL) : in select resistant cases
      • Ongoing research and trials continue to expand its use to other cancers
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      Give for life

      Why Choose Mar Sleeva Medicity Palai?

      • Specialized Infrastructure: Advanced cell-processing laboratories and protective patient-care units designed for intensive monitoring.
      • Expert Multidisciplinary Team: Hemato-oncologists, immunotherapy specialists, genetic scientists, and critical care experts work together for safe and effective outcomes.
      • Cutting-edge Monitoring: Continuous patient observation for early detection and management of therapy-related side effects, such as cytokine release syndrome (CRS).
      • Comprehensive Supportive Care: Includes infection prophylaxis, transfusion services, rehabilitation, and psychological counseling.
      • Global Protocols, Local Access: Treatment protocols adhere to international standards while remaining accessible to patients in India.

      The Treatment Journey

      • Evaluation & Eligibility : Careful assessment of medical history, disease status, and overall health.
      • Cell Collection & Engineering : T cells are harvested and genetically modified using advanced laboratory processes.
      • Conditioning Therapy : Low-dose chemotherapy prepares the body for CAR-T infusion.
      • CAR-T Infusion : Modified cells are returned to the patient’s body in a single infusion.
      • Monitoring & Recovery : Intensive observation for immune responses and side effects, followed by rehabilitation and long-term follow-up.
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      Give for life

      Long-Term Follow-Up

      CAR-T therapy requires ongoing monitoring to:

      • Ensure continued effectiveness of infused CAR-T cells
      • Detect and manage late side effects
      • Support immune system recovery with vaccination schedules and infection control
      • Provide psychological and nutritional support for holistic recovery

      Safety and Expertise

      Our sarcoma surgeries are performed with strict adherence to oncological safety principes, advanced operative technology, and multidisciplinary support. The team ensures maximal tumor removal while preserving limb and organ function.

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      Frequently asked Questions

      You can book an appointment with Dr. Vishnu Mohan, pulse diagnosis doctor in Kerala, through the Mar Sleeva Medicity Palai website at marsleevamedicity.com/book-an-appointment or by calling 04822 359 900.
      Pulse diagnosis helps guide treatment for chronic pain, digestive disorders, metabolic conditions, stress related illness, sleep issues, and lifestyle related imbalances. Dr. Vishnu Mohan combines the insights of Nadivaidyam with acupuncture, diet therapy and herbal therapy for holistic recovery.
      Nadivaidyam is a traditional diagnostic method where the physician reads the rhythm, strength and quality of the pulse to assess the state of different organ systems and identify imbalances in the body. Dr. Vishnu Mohan uses Nadivaidyam to build personalised naturopathy and lifestyle treatment plans.
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