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Total Body and Marrow Irradiation (TBI & TMLI)

      What is Total Body and Marrow Irradiation (TBI & TMLI)?

      Total Body Irradiation (TBI) and Total Marrow and Lymphoid Irradiation (TMLI) are specialized radiation therapies used as part of conditioning regimens before stem cell or bone marrow transplantation. These treatments help eliminate cancerous cells, suppress the immune system to prevent transplant rejection, and prepare the body to accept healthy donor stem cells.

      How TBI & TMLI Works?

      • TBI: Delivers uniform radiation across the entire body to destroy residual cancer cells and immune cells that could interfere with transplantation.
      • TMLI: A more targeted approach that focuses radiation on the bone marrow and lymphoid tissues while sparing other organs, reducing treatment-related toxicity.

      Advanced imaging and computer-guided planning ensure precise dose delivery, protecting vital organs such as the lungs, liver, kidneys, and gastrointestinal tract.

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      Advantages of TBI & TMLI

      • Effective Conditioning: Prepares the body for successful stem cell or bone marrow transplant.
      • Reduced Toxicity (TMLI): Targets only necessary tissues, minimizing side effects compared to traditional TBI.
      • Enhanced Treatment Outcomes: Improves engraftment rates and reduces the risk of relapse in high-risk hematologic malignancies.

      Who Can Benefit from TBI & TMLI?

      Patients undergoing allogeneic or autologous stem cell transplantation for:

        • Leukemia
        • Lymphoma
        • Multiple myeloma
        • Other hematologic malignancies
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      Treatment Process

      • Consultation: Hematology and radiation oncology teams evaluate the patient’s condition and transplant plan.
      • Imaging and Planning: High-precision CT and MRI scans map the target tissues while protecting vital organs.
      • Radiation Delivery: Using advanced linear accelerators, TBI or TMLI is administered over multiple sessions according to the transplant protocol.
      • Monitoring and Support: Patients are closely monitored for treatment tolerance and side effects as part of the transplant journey.

      Safety and Technology

      TBI and TMLI are delivered under strict AERB (Atomic Energy Regulatory Board) guidelines. At Mar Sleeva Medicity Palai, we use cutting-edge imaging and planning systems to optimize dose delivery, ensuring patient safety while maximizing treatment effectiveness.

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      Integration with Stem Cell & Bone Marrow Transplant Program

      TBI and TMLI are integral to our Stem Cell & Bone Marrow Transplant Program, providing patients with a comprehensive, multidisciplinary approach. Our team of hematologists, radiation oncologists, and transplant specialists work together to ensure safe, precise, and effective conditioning therapy before transplantation.

      Why Choose Mar Sleeva Medicity Palai?

      • Expert Hemato-Oncology and Radiation Oncology teams
      • State-of-the-art technology for TBI and TMLI
      • Personalized care plans tailored to transplant protocols
      • Continuous support throughout the transplant journey
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      Frequently asked Questions

      Yes, pharmacy services are available round the clock on premises.

      We are located at Cherpunkal, Pala, Kottayam Dist, Kerala. You may also choose to search us on Google maps as Mar Sleeva Medicity Palai.

      Usually our hospital visiting time is 7.00 AM to 8.00 AM and 5.00 PM to 7.00 PM from Monday to Saturday and Sundays 12.00 Noon to 1.00 PM and 5.00 PM to 7.00 PM. Currently, visitors are restricted due to Covid 19 pandemic situation.

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      We provide the most affordable treatment in the health sector.

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      Critical Medical Care

      Critical medical care for people who have life-threatening injuries and illnesses.